![]() ![]() Set the box so the bottles open from the top and place some kibble inside each bottle.If you cut the hole slightly smaller than the border you traced, the narrow bands in the plastic bottle will help hold it in place without having to glue or tape it. Use the utility knife to cut holes in the box top.Repeat it in different locations on the box top-one for each bottle. Next, trace around one of the water bottles on the top of the box.Vary the height at which you make the cuts to make things more challenging for your cat-easy, medium or difficult. Use your utility knife to cleanly cut the tops off each of the bottles.Duct tape or a non-toxic glue, just in case.Three or more plastic water or soda bottles (8 to 24 ounces).Widen the holes as needed to ensure kibble can pass through. Place some kibble inside the holiday egg, reassemble it and give it a test before rolling it out for play.Next, trim away any remnant plastic so the opening is as free as can be. ![]() Cut a couple holes in the top and bottom section of the holiday egg using the utility knife.A small- to medium-sized plastic holiday egg.Place some kibble in the bottle, screw on the cap and let your cat get to work.Use an utility knife to cut a few small holes in the sides of the container that are large enough for kibble to pass through.A plastic water or soda bottle (8 to 24 ounces).This alters the way that the feeder rolls and adds variety to the experience for your cat. ![]()
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![]() Study Objectives: Verify and characterize abnormally expressed vitreous proteins in adults with full thickness macular holes (MH) versus vitreous from a floaterectomy control group.ĭescription: Randomized Trial Comparing Immediate versus Deferred Surgery for Symptomatic Epiretinal Membranes Despite improved glycemic control for many patients, Diabetic Retinopathy progresses in a large majority of patientsĭescription: Vitreous Proteomics in Eyes with a Macular Hole Study Objectives: To assess the ability of oral Fenofibrate to prevent progression of Diabetic Retinopathy in an at risk population (mild to moderately-severe NPDR). Pathology: Non-Proliferative Diabetic Retinopathy (NPDR)ĭescription: A Randomized Clinical Trial Evaluating Fenofibrate for Prevention of Diabetic Retinopathy Worsening Study Objectives: To determine the efficacy of intravitreal 2.0 mg OPT-302 when administered in combination with intravitreal 2.0 mg aflibercept, in participants with neovascular AMD Pathology: Neovascular Age-Related Macular Degeneration (nAMD)ĭescription: A Phase 3, multicentre, double-masked, randomized study to evaluate the efficacy and safety of intravitreal OPT-302 in combination with aflibercept, between changes in retina function with the severity of diabetic retinopathy. ![]() Study Objectives: The primary objective is to evaluate the safety and tolerability of single and multiple intravitreal injection(s) of OLX10212 in patients with neovascular AMD. Pathology: Wet Age-Related Macular Degeneration (AMD)ĭescription: A Phase 1, Multicenter, Open-Label, Single- and Multi-Dose, Dose-Escalating Clinical Study to Evaluate the Safety and Tolerability of OLX10212 Administered by Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration Study Objectives: To evaluate the efficacy of QA102 oral capsules on the development/progression of geographic atrophy and/or development of CNV in patients with intermediate to small lesion advanced dry AMD. We are also actively involved in retinal research and clinical trials.Pathology: High Risk Intermediate Age-Related Macular Degeneration (AMD) or Small Lesion Geographic Atrophy (GA)ĭescription: A Phase 2, Double-Masked, Randomized, Placebo-Controlled, Dose-Response Study Assessing the Safety and Efficacy of AQ102 in Subjects with dry AMD Our on-call physician and triage staff are available 24/7 after hours, on weekends, and on holidays for emergencies. Treatments include vitrectomy, scleral buckle, and intravitreal injections (Avastin, Eylea, Lucentis, Vabysmo, etc.). ![]() Our retinal specialists and surgeons treat multiple vitreoretinal conditions, including age-related macular degeneration (AMD), diabetic retinopathy, retinal tears and detachments, macular holes and puckers, flashes and floaters, pediatric retinal conditions, and more. We have eight retina centers throughout South Carolina in Beaufort, Ladson, Lake City, Mount Pleasant, Orangeburg, and Walterboro, as well as two in Charleston (West Ashley and The Cigar Factory).Īll of our retina centers feature state-of-the-art diagnostic and testing techniques, like fluorescein angiography and optical computed tomography (OCT). ![]() ![]() God, long as you don’t mind satire, tweets like “ I’m damning things. Tweetīest twitter accounts when you need a break from reality 11. She provides followers with goofy observations about everyday life. Mindy Kaling, Kaling is an actor, writer, producer, and director known for The Mindy Project as well as her work on The Office. Donni Saphire, Donni, a Chicago based comedian and writer, for funny, often absurdist tidbits like “ ‘Hop in the shower.’ -Kangaroo shower advice” and “ Armed to the teeth with tiny tooth arms.” Tweet 10. Jennings’ tweets are almost exclusively jokes - punny dad humor: “ I don’t know anything about dogs but someday I want to own a whippet named Devo.” Tweet 9. Ken Jennings, holder of the longest-ever winning streak and the title of Greatest of All Time (GOAT) Jeopardy contestant also happens to be darn hilarious on Twitter. His humor is mostly topical, so when you’re burned out on current events, pop over to his timeline for a humorous spin on the news. Stephen Colbert, difficult not to be amused by Stephen Colbert’s goofy, throwaway takes on just about anything. Pour Me Coffee, Me Coffee’s goal is to be “Funny and/or interesting.” And that’s just what he delivers - in the form of political satire, interesting facts, images, and wry takes on current events and sports.ĭespite his popularity, no one knows who is behind the account. He once wrote, “ When the phone rings at Meryl Streep’s house, do you think she says, ‘Don’t answer it, it’s just another one of those Oscar nominations?’“Īnd sometimes he’s a bit more random: “ When someone calls me pretentious, the white gloves come off.” Either way, he’s always funny. Conan O’Brien, late-night host and television funnyman is often topical. Take this one for example: “ I’ve memorized all the digits of pi. ![]() Al Yankovic, know him as Weird Al, and his tweets are as goofy-smart as his song parodies. Kat Dennings, actress and star of Two Broke Girls was once a prolific blogger, so it’s no surprise that she shines in 140 characters (or even less).ĭennings’ feed is a regular stream of funny observations about movies, pop culture, and her life, with both earnest and heartwarming-but-still-goofy tweets thrown in every once in a while for good measure. Tim Siedell, Siedell is a Nebraska based creative director and blogger who tweets funny (and punny) things like “ Just downloaded dinner from PDF Chang’s.” Tweet 3. Recently, he made us jealous over his family’s Christmas dinner. ![]() Steve Martin, funnyman Steve Martin also knows how to compose a joke in tweet form - or just give us the warm fuzzies. Best Twitter accounts to follow for a good laugh 1. ![]() ![]() One leak expert estimates that “slightly less than 100% of patients with spontaneous CSF leaks have an underlying connective tissue disorder.” The dura is made out of connective tissue and patients with HDCT’s have thinner dura mater, that is more susceptible to tears and leaks. Heritable Disorders of Connective Tissues ( HDCT’s) such as Marfan Syndrome, Ehlers-Danlos Syndrome (both classical and hypermobility type), autosomal dominant Polycystic Kidney Disease, and other HDCT’s predispose patients to CSF leaks. There is growing evidence suggesting that a significant number of spontaneous CSF leaks occur as the result of a preexisting weakness in the dura. These leaks are usually ventral (or in front of the spinal cord). Sometimes spontaneous leaks may be associated with some sort of spinal pathologies such as calcified disk material or bone spurs. Spontaneous leaks that occur with minimal or no clear cause.Traumatic injuries such as brachial plexus injuries falls, sports injuries, motor vehicle accidents, roller coaster rides, and other whiplash injuries.Medical procedures (also called iatrogenic leaks) for various diagnostic or therapeutic reasons such as lumbar punctures to collect fluid for analysis if meningitis is suspected, lumbar puncture for injection of contrast (myelography), spinal anesthesia, epidural injections, epidural steroid injections, prior skull base or spinal surgery, CSF shunt over-drainage, prior sinonasal surgery, and chiropractic or other spinal manipulations.Some patients have had unnecessary decompression surgeries when the underlying, sole cause was a leak all along. A leak can cause an acquired Chiari malformation or coexist and complicate an existing congenital Chiari malformation. ![]() To make diagnosis even more complex and elusive, CSF leaks can and do often occur along with any of these disorders and perhaps several simultaneously. Some of those common misdiagnoses are Postural Orthostatic Tachycardia Syndrome (POTS), migraines, sinus headaches, Meniere’s Disease, Chronic Fatigue Syndrome, Parkinson’s Disease (sometimes other neurodegenerative diseases), Fibromyalgia, Ehlers-Danlos Syndrome, Tarlov Cyst, Chiari Malformation, Cervical Spine Disease, cervicogenic headache, tension headache, and Sinusitis. ![]() Many who are leaking are not even aware that they are leaking. Other times, especially (but not always) in the case of chronic leaks, the positional symptoms either lessen or go away altogether, including the headache. Imaging and other tests used to attempt to find leaks are often read as “normal” even when there is a leak present. Approximately 50% of leaks cannot be found on imaging. Rare signs or complications of CSF leaks can include: quadriplegia, dementia (often mimicking Frontotemporal Lobe Dementia), Parkinsonism, other movement disorders, ataxia (unsteady gait), hypersomnolence, stupor, coma, stroke (hemorrhagic or ischemic), and even death.ĬSF leaks are often very hard to locate, if ever. Cranial leak specific symptoms can vary even more and can include: fluid discharge from ears, nose (usually only one side) and to back of throat often reported as salty or metallic tasting, recurring or chronic meningitis, loss of sense of smell, change in hearing or ringing in the ears, and less frequently cognitive changes. Other leak symptoms can include, but are not limited to: nausea, vomiting, neck pain or stiffness, heaviness of head, pain between the shoulder blades, feeling of pressure within the head, changes in hearing (muffled or underwater sensation), tinnitus (ringing, buzzing, or pulsatile), feeling of liquid in the ears, sense of imbalance, sensitivity to light, sensitivity to sound, pain or numbness in the arms, changes in cognition (“ brain fog,” memory loss, or loss of concentration), dizziness or vertigo, scalp sensitivity or tingling sensation within the scalp, visual changes (blurring, double vision, visual field defects), pain behind the eyes or when moving eyes, facial numbness or pain, sinus pressure, temporomandibular joint pain and stiffness, and subdural hematoma. Symptoms often worsen as the day goes on. ![]() This is particularly the case in the chronic (vs acute) phase of CSF leaks, where the “positional” or “orthostatic” characteristic of symptoms may become more constant, lessen, or disappear entirely, including headache. However, not all positional headaches can be attributed to a CSF leak, and not all CSF leak headaches are positional. This is sometimes called a “positional” or “orthostatic” headache. ![]() The main symptom of a CSF leak is a headache that is worse when upright and improves when lying down horizontally. ![]() ![]()
![]() Today, as he does every day, Tango Tanimura is in his workshop, pursuing his quest to produce ever-higher quality chasen. ![]() His primary concern is how to create something that is easy to use.įor him, a chasen is a vehicle to make people happy by contributing to a wonderful tea ceremony. When Tango Tanimura works with his bamboo he only has its user in mind. Simply carving and shaping bamboo like a whisk does not really justify calling it a chasen, does it? Most of these whisk makers do not really understand how their whisk is going to be used, nor do they have any means to communicate with users. In today’s interconnected world, is it quite easy to buy cheap, foreign tea whisks. Direct interaction with the actual users of their chasen provides a line of praise and criticism, which in turn serves a basis for improvement and goals to work towards. One house of chasen masters, the Tanimura family has upheld this intricate art for five centuries. “Art” is indeed the right word, because this process of creating balance, for which Tango Tanimura relies solely on the intricate feeling in his fingertips, cannot rightfully be called anything else.Īlthough many chasen masters in Takayama sell to wholesale dealers, the Tanimura family has for generations delivered their products directly to the head families of the various schools of tea ceremony. BAMBOO TEA WHISKS TANGO TANIMURA AND THE HEART OF CHASEN Witness the 500 Year old Secret Art of Tea Whisk Making The Art of Contrast The 500-year-old art of chasen, or tea whisks from Takayama, Nara. Maintaining a meticulous balance between these two elements is the secret to the art that the Tanimura family has honed for more than half a millennium. In order to create flexible tips, the wood needs to be cut very thinly, but the thinner the wood, the less durable it becomes. However, these two elements seem to contradict each other. The Tanimura family is devoted to making sturdy and easy-to-use chasen.Įasy usage is defined by elastic and flexible tips, while sturdiness refers to the whisks’ durability. ![]() When Tango Tanimura was announced as the 20th-generation successor to the family line, history weighed heavy on him, but he was buoyed by gratitude to his forebears. The 500-year-old art of chasen, or “tea whisks” from Takayama, Nara. ![]() ![]() ![]() The first line he ever collected was Mego’s World’s Greatest Super Heroes line back in the 70s. I love that all Star Wars characters have cool backstories, no matter how briefly they appear, it wasn’t easy to decide which characters to include in the set, but we hope fans will love the entire model and its line-up of heroes and villains.”ĪFi founder and Editor-In-Chief Daniel “Julius Marx” Pickett has been around toys his whole life. With this design, we’ve added external buildings like the Jawa shop, refined the details, and chosen an impressive 21 minifigure characters, including all-new alien figures. I remember thinking, ‘this is where the adventure starts!’ Years later, when I then became a LEGO® Star Wars ™ designer in 2016, this was the first set I built. “The first time I watched the cantina scene in Star Wars: A New Hope, I was just 12 years old. Speaking about the creative process behind the new building kit, set designer Cesar Soares said: ![]() Part of the Master Builder series, the new Star Wars building kit is the latest example of how the LEGO Group aims to inspire builders to build, rebuild and get excited by the process of creation. Once built, the 3,187-piece LEGO® Star Wars Mos Eisley Cantina™ construction set makes for an extraordinary display piece, standing at over 7.5” (19cm) high, 20.5” (52cm) wide and 23” (58cm) deep when opened. The LEGO® Star Wars Mos Eisley Cantina™ is also dotted with hidden details throughout, such a “Wanted” poster featuring R2-D2 and C-3PO, to the kyber crystals hidden in one of the exterior buildings. EvazanTM, GarindanTM, and more.Īs they embark on their journey to bring Mos Eisley’s quintessential taverna to life, films lovers and Star Wars devotees will be thrilled to discover the set’s special features, such as the attachable buildings, two landspeeders – one of which has never been built in LEGO before – and a dewback LEGO Star Wars figure. Additionally, the set features eight character mini-figures that have been introduced in LEGO form for the first time, including Ponda BabaTM, Dr. ![]() Intrepid builders can even open up the set’s removable roof to admire its intricate details and act out their favourite Star Wars: A New Hope scenes, using iconic character mini-figures including Luke SkywalkerTM, Han SoloTM, C-3POTM. The impressive building kit gives adult LEGO fans the chance to relax and enjoy a mindful building experience as they reconnect with their passion for the original trilogy. Bringing to life one of the Skywalker saga’s most iconic locations, the new set is sure to become an instant classic as fans immerse themselves in the famous cantina’s world of smugglers, musicians, bounty hunters and Jedi Knights. ![]() To make the deal even sweeter, it looks like there’s going to be a Yoda’s Lightsaber GWP (Gift With Purchase) when you purchase the set, while stocks last of course.Billund, September 9, 2020: Coming from a galaxy far, far away and into to the homes of LEGO enthusiasts and Star Wars fans across the world – the LEGO Group’s new LEGO® Star Wars building set, the Mos Eisley Cantina™ set, will dazzle adult builders and film fans alike. In fact, the set will be retailing for US$349.90 and will be available on 1 October 2020. With how big this Star Wars LEGO set is, it is no surprise that it will cost you quite a fair bit too. The set will also come with a removable roof to give you easy access to the different booths in the collection so that you can explore and play out stories according to your fancy. Evazan, the droid-racist barman, Garindan the snitch, and the cantina band Figrin D’an and the Modal Nodes.Īccording to Nerdist, the set will stand over 19cm tall, and 58cm deep when opened up. Other characters that you will get in the set includes Ponda Baba, Dr. What’s more, the set will also come with 21 minifigs for you to play around with, so not only will you be able to recreate the scene where Obi-Wan and Luke recruits Han Solo and Chewbacca, but also have Han Solo engage in a shootout with Greedo. The set comes with 3187 pieces, to let you build not only the cantina and outbuildings but also two landspeeders and a dewback. ![]() ![]() ![]() What are the Top 10 largest Powerball jackpots ever? ![]() The overall odds of winning a lesser Mega Millions prize are 1 in 24. To win the jackpot, the odds of getting all six different numbers correct is 1 in 302,575,350. What are the odds of winning the Mega Millions? In Florida, beginning May 25, 2022, the names of Lottery winners claiming prizes of $250,000 or greater will be temporarily exempt from public disclosure for 90 days from the date the prize is claimed, unless otherwise waived by the winner. In Florida, 80 percent of all unclaimed jackpot prizes are transferred to the Educational Enhancement Trust Fund to benefit education in the state. What happens to the money if a Mega Millions jackpot ticket is won in Florida but is not claimed?Īt the end of the winning state's claim period (180 days in Florida), the funds to pay a jackpot that go unclaimed will be returned to the lottery members in their proportion of sales for the jackpot rollover series. All Mega Millions prizes must be claimed in the state where the ticket was purchased. If there is no jackpot winner, the money in the jackpot pool rolls over to the next drawing.Īll prizes must be claimed within 180 days of the applicable drawing date. Jackpot winners may elect to receive their winning in a one-time cash payment or 30 graduated annual installments. How is a Mega Millions winner paid?Īll Mega Millions prizes, excluding the jackpot, will be a one-time cash payment less applicable taxes. Any additional federal, state and/or local taxes shall be the responsibility of the winner. Are lottery winnings subject to taxation?įederal income taxes will be withheld from Mega Million prizes, as required by the Internal Revenue Code. Tickets purchased after that time will be for the next drawing. In Florida, tickets may be purchased until 10 p.m. How late can you buy a Mega Millions ticket in Florida? You can watch the drawings on official Florida Lottery TV carrier stations, on the Florida Lottery official website, at Florida Lottery retailers statewide, and by phone at (850) 921-PLAY. Where can I view the Mega Millions drawings? When are Mega Millions drawings held?ĭrawings are held Tuesday and Friday nights at 11 p.m. The next drawing for Mega Millions will be held at 11 p.m. When is the next drawing for Mega Millions? How much do Mega Millions tickets cost?Ī ticket is $2 per play. Pick up a ticket at an authorized Florida Lottery retailer, use a Florida Lottery mobile app to create a digital playslip, or purchase a QUICKTICKET™ in the check-out lane at select Lottery retail locations. No winner, jackpot grows to $325M Where can I buy a ticket? ![]() Powerball numbers: Winning Powerball numbers for Wednesday, Jan. Winning numbers: Mega Millions lottery jackpot climbs to nearly $1 billion no winner in Tuesday drawing The cash option for the winning numbers is $483.5 million.Ĭheck your Mega Millions numbers: Will anyone claim the $940 million jackpot from this drawing? The jackpot for Friday's drawing is at $940 million. Here's everything you need to know about the drawing. The odds may be steep (1 in 302,575,350), but winning would certainly be a real life changer. With the fourth biggest jackpot in Mega Millions history up for grabs on Friday night, plenty of folks are plunking down $2 for a chance to win big. There are about 940 million reasons why you should buy a Mega Millions ticket for Friday's drawing. The winning numbers for the October 14 Mega Millions drawing were 09-22-26-41-44 and the Mega Ball was 19.View Gallery: Top 10 largest Powerball, Mega Millions lottery jackpot winners, photos Winners in Florida cannot remain anonymous, according to the Florida Lottery. The Florida winner has 180 days to make a claim on the prize. “We’re hopeful that the prize will have a positive impact on both the jackpot winner and the retailer who sold the winning ticket,” Davis said. “While we are always thrilled for all our winners, this win feels slightly more meaningful than others since the winning ticket was purchased in Fort Myers, an area that is still undergoing restoration efforts due to the impact from Hurricane Ian several weeks ago,” Florida Lottery Secretary John F. Ian is expected to be the most expensive storm in Florida’s history. Lee County, home of Fort Myers, recorded more than 50 storm deaths, according to local officials. Fort Myers Beach saw “total devastation,” Fort Myers Beach Town Council Member Dan Allers said afterward. But the area around Fort Myers was hardest hit. The area around the 7-Eleven in Fort Myers was affected by the hurricane, according to CNN’s Carlos Suarez who reported from the area after the storm made landfall.Ī powerful Category 4 storm, Ian left more than 100 people dead in Florida and devastated neighborhoods along the state’s west coast as well as inland cities – including Orlando. In pictures: Hurricane Ian slams the Southeast ![]() ![]() and send their application to the UK Border Agency for approval. We’ll also capture a digital copy of your signature. When you apply for permission for a visa or permission to remain in the UK, we will scan your fingers and thumbs (10 digits) and photograph your face digitally. ![]() Those receiving benefits, state pensions and tax credit payments can collect their cash using our Post Office Card Accounts and over 3 million currently do.įoreign nationals applying for residency in the UK can now use our advanced biometric data capture booths in around 100 of our branches, to enrol their biometricsYour biometric information (sometimes called 'biometrics') is the set of unique physical characteristics that can be used to identify you. Error rates with this service offered at our branches are consistently between 1% and 2%, compared to over 10% for applications sent direct to the Identity and Passport Service. Motorists can use one of our 750 Application, Enrolment and Identification (AEI) booths to renew their Photocard Driving Licence for 10 years.Īnyone applying for a new, renewal or replacement passport can use our Passport Check & Send service. ![]() We provide a range of services for governmental departments and local councils. It’s not just about access though, by using us as your front office you’ll reduce fraud though identity verification, improve the quality and accuracy of applications and reduce paper handling.
![]() Final product details may change from the images shown. Please note that if you add any additional items in the Official Warframe Store to your order, they will also ship in early 2019. These items are expected to ship in late March, 2019. The Sacrifice merchandise is only available to purchase until November 9, so get yours today before it’s too late! Click here to pre-order your Sacrifice collector’s items now! Purchase these items in the bundle and save! Includes the Excalibur Umbra Collector’s Statue, the limited-edition Vitruvian T-shirt and the in-game code for an Excalibur Umbra Noggle and 170 Platinum. Take away the pain with the limited-edition Sacrifice Collection. But as with many things the Orokin created. It was a 20 minute pain-in-the-ass, but still do-able. This Vitruvian-inspired T-shirt is premium quality, cut and sewn, and made with 100% polyester. The Orokin Towers are symbols of dominance and glory, testaments to the Orokins mastery of space and substance. Youll need to do Eidolon Hunts (or farm a fLOAD of Vomvalysts) to get standing, along with fishing/minding/cetus wisp farming to build an Amp, but even the most basic of Amps is a hell of a lot better than the Mote Amp. Honor the Sacrifice with this limited edition T-shirt. As an added bonus, every Umbra Collector's Statue includes a code for an Excalibur Umbra Noggle for your Orbiter and 170 Platinum! Created in partnership with Happy Worker Toys, the 9” statue is crafted from high-quality polyresin, meticulously cast and hand-painted. This limited-edition statue depicts Excalibur Umbra, the tortured Warframe at the heart of The Sacrifice, on the prowl with his signature Nikana in hand. On at 10:18 PM, Dr.Enthu said: Whats the next umbral frame None, because Umbra was the name of the Dax Soldier that was turned into a Warframe for witnessing Ballas betrayal by giving Orokin secrets to the Sentients. Save money when you purchase these items as a bundle, or you can buy them individually!Įxcalibur Umbra Limited-Edition Collector’s Statue In celebration of our latest cinematic Quest, this limited-edition collection includes a high-quality 9” Excalibur Umbra Collector’s Statue and an exclusive Vitruvian T-shirt. The Sacrifice Collection is available now to pre-order here. Its likely that like Umbra, whatever other warframe Variant that came would inherit the name of the individual used. Howl all you want, it won’t bring him back.but it will bring you limited-edition Warframe merch! On at 10:18 PM, Dr.Enthu said: Whats the next umbral frame None, because Umbra was the name of the Dax Soldier that was turned into a Warframe for witnessing Ballas betrayal by giving Orokin secrets to the Sentients. ![]() |
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